Knowledge and Skills Statement
Genetic drift occurs in all populations, but its effects are most visible in smaller populations. Because fewer members of the population hold any given trait, the reproduction of any member can have a large effect on the allele frequencies within the population. Some alleles may increase in frequency, or some alleles may decrease or disappear by random chance.
While students may readily relate to gene flow as migration, it is also beneficial to provide examples outside of the animal kingdom such as pollen being blown across a continent or the spread of viral lineages across the world.
Mutations can be caused by errors in DNA replication, which can substitute one nucleotide for another, and by chemicals or radiation, which change the structure of individual nucleotides.
Genetic recombination is the exchange of genetic material between organisms. Recombination increases the genetic diversity of a population by generating different combinations of alleles in the offspring from those that were present in the parents. Recombination occurs during meiosis in eukaryotic, sexually reproducing organisms. It can also occur in bacteria and archaea via transformation (uptake of free DNA from the environment), transduction (virus-mediated DNA transfer), or conjugation (transfer of DNA via cell-to-cell contact), and is the main method of diversification in RNA viruses. V(D)J recombination occurs in organisms with an adaptive immune system and is a type of site-specific genetic recombination that helps immune cells rapidly diversify to recognize and adapt to new pathogens. Recombination is used extensively in laboratory research, vaccine development, and genetic engineering.
Research
Melicher, Dacotah, and Julia H. Bowsher. "Exploring the Evolutionary History of a Novel Trait in Sepsidae." Proceedings of the North Dakota Academy of Science 69, (April 2015): 44A.
Summary: The novel abdominal appendage in male sepsid flies (Diptera: Sepsidae) has a complex evolutionary history of primary gain, loss, and regain which we explore using fluorescent microscopy to compare the size, volume, and number of cells in the histoblast cell nests that produce the appendage during pupation across six genera including an ancestral outgroup which describe the evolutionary history of the appendage.
Research
Yang, Shimin, Jianyu Chen, Jinjian Fu, Jiayin Huang, Ting Li, Zhenjiang Yao, and Xiaohua Ye. "Disease-Associated Streptococcus pneumoniae Genetic Variation." Emerging Infectious Diseases 30, no. 1 (January 2024): 39-49. https://doi.org/10.3201/eid3001.221927
Summary: Streptococcus pneumoniae is an opportunistic pathogen that causes substantial illness and death among children worldwide. To determine the evolutionary mechanisms of opportunistic pathogenicity, we conducted a genomic surveillance study in China. Our findings suggest that S. pneumoniae pathogenicity is complex and multifactorial, and we provide genetic evidence for precise targeted interventions.